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Functional Proteomics - CBMS833

Functional proteomics is the study of protein expression in living systems, considered in a functional context. This allows us to better understand how protein networks become dysfunctional, which in turn enables the manipulation of protein functions and cellular phenotypes through the use of drug treatment, or genetic or environmental intervention. This unit covers the principles and applications of functional proteomic techniques, and assumes basic knowledge of protein electrophoresis and mass spectrometry. Topics include: a detailed study of advanced techniques, instrumentation and protein identification software in mass spectrometry; two-dimensional differential gel electrophoresis; label-free and isotope-labelling quantitation in proteomics; application of different types of peptide- and protein-based shotgun proteomics approaches; characterisation of protein post-translational modifications including phosphorylation, glycosylation and others; and application of proteomics in the pharmaceutical industry. Students must attend a compulsory one week laboratory session during the session break.

Credit Points: 4
When Offered:

S2 Day - Session 2, North Ryde, Day

Staff Contact(s): Professor Paul Haynes

Admission to MBiotech or MBiotechMCom or MLabQAMgt or MRadiopharmSc or MMarScMgt or MBioBus or MSc Prerequisite Information


Unit Designation(s):


Assessed As: Graded
Offered By:

Department of Chemistry and Biomolecular Sciences

Faculty of Science and Engineering

Course structures, including unit offerings, are subject to change.
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