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Medicinal Chemistry - CBMS842
This unit starts with an overview of the structure and function of important biomolecules that are drug targets and then focuses on how drugs interact with these molecules to bring about their pharmacological activity. The aim of the unit is to integrate chemical biology and organic chemistry to reveal how these are used in medicinal chemistry to design and synthesise new drugs and to understand their mode of action. Case studies are also provided, including antibacterial, psychoactive and anticancer agents. The theory is complemented by a discovery-based laboratory project incorporating synthetic chemistry, spectroscopic and bioassay methods. The unique aspect of this unit is the focus on computational chemistry in drug design and development. This includes aspects of molecular modelling, molecular dynamics, docking, pharmacophore modelling and QSAR as they relate to the understanding of drug action and design of new drugs.
| Credit Points: | 4 |
| When Offered: | S1 Day - Session 1, North Ryde, Day |
| Staff Contact(s): | Professor Peter Karuso |
| Prerequisites: |
(Admission to MBiotech or MLabQAMgt or PGDipLabQAMgt or PGCertLabQAMgt or MRadiopharmSc or MSc) and permission of Executive Dean of Faculty |
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| NCCW(s): | |
| Unit Designation(s): | |
| Assessed As: | Graded |
| Offered By: | Department of Chemistry and Biomolecular Sciences Faculty of Science |
Timetable Information
For unit timetable information and session dates for external offerings please visit the Timetables@Macquarie Website.