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CBMS333: Functional Proteomics
Functional proteomics is the study of protein expression in living systems, considered in a functional context. This allows us to better understand how protein networks become dysfunctional, which in turn enables the manipulation of protein functions and cellular phenotypes through the use of drug treatment, or genetic or environmental intervention. This unit covers the principles and applications of functional proteomic techniques, and assumes basic knowledge of protein electrophoresis and mass spectrometry. Topics covered include: a detailed study of advanced techniques, instrumentation and protein identification software in mass spectrometry; two dimensional differential gel electrophoresis; label-free and isotope-labelling quantitation in proteomics; application of different types of peptide- and protein-based shotgun proteomics approaches; characterisation of protein post-translational modifications including phosphorylation, glycosylation and others; and application of proteomics in the pharmaceutical industry.
| Credit Points: | 3 |
| Contact Hours: | 7 |
| When Offered: | D2 - Day; Offered in the second half-year |
| Staff Contact(s): | Associate Professor Paul Haynes |
| Prerequisites: |
CBMS332(P) |
| Corequisites: | |
| NCCW(s): | CBMS833 |
| Unit Designation(s): | |
| Assessed As: | Graded |
| Offered By: | Department of Chemistry and Biomolecular Sciences |
Timetable Information
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